Miami Mice Research Mouse models

Miami Mice Research has the following Cre transgenic mice and mouse models of disease.

Please contact Dr. Corrinne Lobe if you would like to obtain or use the mice.

CreERt	Widespread expression of tamoxifen-inducible Cre recombinase. Available to researchers.	A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action.Guo C, Yang W, Lobe CG. Genesis. 2002 Jan;32(1):8-18
Grg1	Mouse model of non-small cell lung cancer. Available for research, drug development and testing.	Grg1 acts as a lung-specific oncogene in a transgenic mouse model. Allen T, van Tuyl M, Iyengar P, Jothy S, Post M, Tsao MS, Lobe CG. Cancer Res. 2006 Feb 1;66(3):1294-301.
IC-Notch	Cre-conditional expression of activated Notch, for studies of angiogenesis, cancer and neural disorders.	Cre-conditional expression of constitutively active Notch1 in transgenic mice. Liu J, Lobe CG. Genesis. 2007 May;45(5):259-65.
ZEG	Reporter mice for Cre activity. Widespread lacZ expression before Cre excision, EGFP expression after Cre excision.	Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Novak A, Guo C, Yang W, Nagy A, Lobe CG. Genesis. 2000 Nov-Dec;28(3-4):147-55.
ZAP	Reporter mice for Cre activity. Widespread lacZ expression before Cre excision, human alkaline phosphatase expression after Cre excision.	Z/AP, a double reporter for cre-mediated recombination. Lobe CG, Koop KE, Kreppner W, Lomeli H, Gertsenstein M, Nagy A. Dev Biol. 1999 Apr 15;208(2):281-92.