Mouse Requests

Please direct requests for mice to the Jackson Labs. http://jaxmice.jax.org/orders/index.html
If you have questions about the mice, contact me at c.lobe@utoronto.ca

For-profit institutes please contact me at c.lobe@utoronto.ca regarding a license to use the mice.

ZAP mice
Strain Name: Tg(ACTB-Bgeo/ALPP)1Lbe/J
Stock Number: 003919
http://jaxmice.jax.org/strain/003919.html

ZEG mice
Strain Name: Tg(ACTB-Bgeo/GFP)21Lbe
Stock Number: 003920
http://jaxmice.jax.org/strain/003920.html

The following lines will be available from Jax soon:

iZAP-Grg1 mice
Strain Name: Tg(ACTB-Tle1,lacZ,ALPP)1Lbe/J
Stock Number: 006613
http://jaxmice.jax.org/strain/006613.html

iZEG-Notch mice
Strain Name: Tg(ACTB-Bgeo,Notch1,EGFP)1Lbe/J
Stock Number: 006850
http://jaxmice.jax.org/strain/006850.html
Mice hemizygous for this Cre-conditional IC-Notch (or Z/EG-Notch) transgene are viable and fertile. Homozygotes die in utero, presumably due to high lacZ expression. Prior to cre-mediated excision of the "floxed" STOP sequence, high expression of lacZ is observed in cells and tissues. These transgenic mice may be useful for global expression of lacZ or, when crossed to a Cre-recombinase expressing strain, for studying the role of Notch signaling during both embryonic development and adulthood.

iZEG-Tel-AML1 mice
Strain Name: Tg(ACTB-Bgeo,TEL/AML1,EGFP)A6Lbe/J
Stock Number: 006876
http://jaxmice.jax.org/strain/006876.html
Mice hemizygous for this Cre-conditional TEL-AML1 (or iZ/EG-TEL-AML1) transgene are viable and fertile. These transgenic mice may be useful for global expression of lacZ or, when crossed to a Cre-recombinase expressing strain, for studying hematopoietic development, cancer, and leukemia.

iZAP-AML1-ETO mice
Strain Name: Tg(ACTB-Bgeo,AML1/ETO,ALPP)1Lbe/J (006882)
Stock Number: 006882
http://jaxmice.jax.org/strain/006882.html
Mice hemizygous for this "Z/AP-AML1-ETO" transgene (coding for the translocation t(8;21) present in 15% of acute myeloid leukemias (AML)) are viable and fertile. These transgenic mice may be useful for global expression of lacZ or, when crossed to a Cre-recombinase expressing strain, for studying hematopoietic development, cancer, and leukemia.